BDBM50029625 1-methyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene::4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1-enyl]-benzenesulfonamide::CHEMBL127674

SMILES Cc1ccc(cc1)C1=C(CCC1)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=DFLFDHXLMTYYEI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029625   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50029625(4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50029625(4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50029625(4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50029625(4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1...)
Affinity DataIC50: 3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed