BDBM50029702 3-Chloro-2-(4-isopropyl-1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethoxy)-pyrido[1,2-a]pyrimidin-4-one::CHEMBL356732

SMILES CC(C)c1cccc2c1C(=O)N(COc1nc3ccccn3c(=O)c1Cl)S2(=O)=O

InChI Key InChIKey=IZOGWZMDGOQIKF-UHFFFAOYSA-N

Data  1 KI  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029702   

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029702(3-Chloro-2-(4-isopropyl-1,1,3-trioxo-1,3-dihydro-1...)
Affinity DataKi:  0.210nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029702(3-Chloro-2-(4-isopropyl-1,1,3-trioxo-1,3-dihydro-1...)
Affinity DataKoff:  4.30E+4s-1Assay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed