BDBM50029793 8-[1-Cyclopropyl-meth-(E)-ylidene]-5-(3-hydroxy-phenyl)-2-methyl-2-aza-bicyclo[3.3.1]nonan-7-one::CHEMBL358527

SMILES CN1CCC2(CC1C(=CC1CC1)C(=O)C2)c1cccc(O)c1

InChI Key InChIKey=HSBXJWCCDJBVER-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029793   

TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029793(8-[1-Cyclopropyl-meth-(E)-ylidene]-5-(3-hydroxy-ph...)
Affinity DataKi:  11.2nMAssay Description:Ability to inhibit [3H]DAMGO binding to rat brain Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029793(8-[1-Cyclopropyl-meth-(E)-ylidene]-5-(3-hydroxy-ph...)
Affinity DataKi:  62.3nMAssay Description:Ability to inhibit [3H](+)-pentazocine binding to guinea pig brain Sigma receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029793(8-[1-Cyclopropyl-meth-(E)-ylidene]-5-(3-hydroxy-ph...)
Affinity DataKi: >500nMAssay Description:Ability to inhibit [3H]U-69593 binding to guinea pig Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029793(8-[1-Cyclopropyl-meth-(E)-ylidene]-5-(3-hydroxy-ph...)
Affinity DataKi: >1.00E+3nMAssay Description:Ability to inhibit [3H]DADLE binding to rat brain delta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed