BDBM50031436 10,13-Dimethyl-4-phenylsulfanyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione::CHEMBL336387

SMILES CC12CCC3C(CCC4=C(Sc5ccccc5)C(=O)CCC34C)C1CCC2=O

InChI Key InChIKey=CLKVUYDHWSHNGQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031436   

TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031436(10,13-Dimethyl-4-phenylsulfanyl-1,6,7,8,9,10,11,12...)
Affinity DataKi:  36nMAssay Description:Evaluated for its competitive inhibitory activity against Cytochrome P450 19A1 with the use of human placental microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031436(10,13-Dimethyl-4-phenylsulfanyl-1,6,7,8,9,10,11,12...)
Affinity DataIC50: 190nMAssay Description:Inhibition of Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed