BDBM50031908 CHEMBL3360906

SMILES Cc1cccc(CSc2nnc(NC(=O)CSc3nc4ccc(cc4s3)N3C(=O)c4ccccc4C3=O)s2)c1

InChI Key InChIKey=YXXHMCHMAVOSQR-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50031908   

TargetTyrosine-protein phosphatase non-receptor type 18(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPN18 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of STEP (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of VHR (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetProtein phosphatase Slingshot homolog 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SSH2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetProtein phosphatase 1A(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of PPM1A (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetProtein phosphatase 1G(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PPM1G (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataKi:  9.97E+3nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed