BDBM50031939 6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-9-oxa-5-aza-benzo[6,7]cyclohepta[1,2-a]naphthalene::CHEMBL62589

SMILES CN1CCN(CC1)c1nc2ccccc2c-2c1CCOc1ccccc-21

InChI Key InChIKey=LQGPXIKYBHFESW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031939   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031939(6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-9-oxa-5-az...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031939(6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-9-oxa-5-az...)
Affinity DataKi:  3.80nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031939(6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-9-oxa-5-az...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 2A receptor from rat cortex assayed using [3H]ketanserin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed