BDBM50032565 (4-Methyl-naphthalen-1-yl)-[1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone::CHEMBL80214

SMILES Cc1ccc(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)c2ccccc12

InChI Key InChIKey=ICKWPPYMDARCKJ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50032565   

TargetCannabinoid receptor 1(Rat)
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032565((4-Methyl-naphthalen-1-yl)-[1-(2-morpholin-4-yl-et...)
Affinity DataIC50: 2.80nMAssay Description:Concentration of compound required to inhibit 50% of [3H]WIN-55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50032565((4-Methyl-naphthalen-1-yl)-[1-(2-morpholin-4-yl-et...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032565((4-Methyl-naphthalen-1-yl)-[1-(2-morpholin-4-yl-et...)
Affinity DataKi:  4.47E+8nMAssay Description:Cannabinoid receptor 1 binding affinity by measuring its ability to displace [3H]WIN-55212-2 in rat forebrain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032565((4-Methyl-naphthalen-1-yl)-[1-(2-morpholin-4-yl-et...)
Affinity DataKi:  4.47E+8nMAssay Description:Binding affinity at cannabinoid receptor 1 using rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed