BDBM50032588 CHEMBL3354167

SMILES CCc1csc2c1nc(NC1CCCC1)n(CC)c2=O

InChI Key InChIKey=BWSIWBJRZRFBBB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032588   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Kyoto 607-8042

Curated by ChEMBL

LigandBDBM50032588(CHEMBL3354167)Copy SMILESCopy InChI

Affinity DataIC50: 42nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/12/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL

LigandBDBM50032588(CHEMBL3354167)Copy SMILESCopy InChI

Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/12/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL