BDBM50032738 CHEMBL3354719

SMILES NC1=N[C@@]2(CO1)c1cc(ccc1Oc1c(F)cc(cc21)N1CCOCC1)-c1cccnc1F

InChI Key InChIKey=IWIBSPRXMYPEGW-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032738   

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL

LigandBDBM50032738(CHEMBL3354719)Copy SMILESCopy InChI

Affinity DataIC50: 5nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/12/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Amgen

Curated by ChEMBL

LigandBDBM50032738(CHEMBL3354719)Copy SMILESCopy InChI

Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human ERG expressing HEK293 cells by [3H]dofetilide binding assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/12/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL