BDBM50033381 CHEMBL3357642

SMILES CN(C)C\C=C(\F)C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1

InChI Key InChIKey=HZBHTRUJNPPRNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033381   

TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50033381(CHEMBL3357642)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50033381(CHEMBL3357642)
Affinity DataIC50: 26nMAssay Description:Inhibition of wild type EGFR T790M mutant (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50033381(CHEMBL3357642)
Affinity DataIC50: 97nMAssay Description:Inhibition of wild type HER2 (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed