BDBM50033434 2-(4-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-acetyl}-piperazin-1-yl)-benzonitrile::CHEMBL119927

SMILES NCCc1c[nH]c2ccc(OCC(=O)N3CCN(CC3)c3ccccc3C#N)cc12

InChI Key InChIKey=GDPQCZJZKFQSEA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033434   

Target5-hydroxytryptamine receptor 1D(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033434(2-(4-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-acety...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity for cloned human 5-hydroxytryptamine 1D receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033434(2-(4-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-acety...)
Affinity DataKi:  0.920nMAssay Description:Binding affinity to recombinant human 5-hydroxytryptamine 1D receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033434(2-(4-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-acety...)
Affinity DataKi:  15nMAssay Description:Binding affinity for cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed