BDBM50034016 (S)-4,11-Diethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,8,12a-triaza-dibenzo[b,h]fluorene-9-carbonitrile::CHEMBL13787

SMILES CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2cnc(cc12)C#N

InChI Key InChIKey=YHFOIKXOOLBZHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034016   

TargetDNA topoisomerase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50034016((S)-4,11-Diethyl-4-hydroxy-3,13-dioxo-3,4,12,13-te...)
Affinity DataIC50: 268nMAssay Description:In vitro fragmentation of DNA in the presence of excess calf thymus topoisomerase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed