BDBM50034022 (S)-4,11-Diethyl-4-hydroxy-8-methyl-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-8-azonia-dibenzo[b,h]fluorene; iodide::CHEMBL13355

SMILES CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2c[n+](C)ccc12

InChI Key InChIKey=RAEIDPGVVIFWEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034022   

TargetDNA topoisomerase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50034022((S)-4,11-Diethyl-4-hydroxy-8-methyl-3,13-dioxo-3,4...)
Affinity DataIC50: 1.46E+3nMAssay Description:Minimum concentration that produced 50% fragmentation of DNA was measured in the presence of excess calf thymus topoisomerase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed