BDBM50034090 CHEMBL3359239

SMILES Cc1nc(nc(OCCCN2CCCCC2)c1Cl)-c1ccc(Cl)cc1

InChI Key InChIKey=MSFUOAXHQLXDAO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50034090   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50034090(CHEMBL3359239)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in Dunkin Hartley guinea pig brain membranes after 180 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50034090(CHEMBL3359239)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from recombinant human sigma1 receptor expressed in HEK293 cell membranes after 120 mins by microbeta scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50034090(CHEMBL3359239)
Affinity DataIC50: 6.98E+3nMAssay Description:Inhibition of ERG channel in HEK293 cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed