BDBM50034841 (S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoyl)-pentanoic acid::CHEMBL45123

SMILES OC(=O)CCNC(=O)[C@@H](CCC(O)=O)Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ARICPHPZNTVQNB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50034841   

TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50034841((S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoyl)-p...)
Affinity DataIC50: 0.700nMAssay Description:The compound was tested in vitro for inhibition of Neutral endopeptidase by using Leu enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50034841((S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoyl)-p...)
Affinity DataIC50: 155nMAssay Description:In vitro inhibition of rat neutral endopeptidase by using GAAP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50034841((S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoyl)-p...)
Affinity DataIC50: 155nMAssay Description:The compound was tested for inhibition of Neutral endopeptidase by using GAAP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed