BDBM50035084 CHEMBL3338292

SMILES Cc1noc(C2CC2)c1Cc1cc(F)ccc1-c1cn(CC(O)=O)c2ccc(cc12)C(F)(F)F

InChI Key InChIKey=XNWLFEZEXPUZOU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035084   

TargetProstaglandin D2 receptor 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50035084(CHEMBL3338292)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50035084(CHEMBL3338292)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed