BDBM50035268 5-((phenylamino)methyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::5-Phenylaminomethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL432136

SMILES Nc1nc(N)c2c(CNc3ccccc3)c[nH]c2n1

InChI Key InChIKey=UMOSRKWZUFNHKM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035268   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035268(5-Phenylaminomethyl-7H-pyrrolo[2,3-d]pyrimidine-2,...)
Affinity DataIC50: 2.52E+5nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035268(5-Phenylaminomethyl-7H-pyrrolo[2,3-d]pyrimidine-2,...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035268(5-Phenylaminomethyl-7H-pyrrolo[2,3-d]pyrimidine-2,...)
Affinity DataIC50: 2.52E+5nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035268(5-Phenylaminomethyl-7H-pyrrolo[2,3-d]pyrimidine-2,...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035268(5-Phenylaminomethyl-7H-pyrrolo[2,3-d]pyrimidine-2,...)
Affinity DataIC50: 2.52E+5nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed