BDBM50035435 4'-[3-Butyl-1-(4-nitro-2-trifluoromethyl-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-chloro-benzoylamide::CHEMBL341715

SMILES CCCCc1nn(-c2ccc(cc2C(F)(F)F)[N+]([O-])=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl

InChI Key InChIKey=NEEKZHLENANADV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035435   

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035435(4'-[3-Butyl-1-(4-nitro-2-trifluoromethyl-phenyl)-5...)
Affinity DataIC50: 1.60nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035435(4'-[3-Butyl-1-(4-nitro-2-trifluoromethyl-phenyl)-5...)
Affinity DataIC50: 190nMAssay Description:In vitro binding affinity against angiotensin II (AT2) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rat mid b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035435(4'-[3-Butyl-1-(4-nitro-2-trifluoromethyl-phenyl)-5...)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at AT1 receptor in rabbit aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article