BDBM50035480 5-Chloro-N*6*-[3-(3,4,5-trimethoxy-phenyl)-propyl]-quinazoline-2,4,6-triamine::CHEMBL141469

SMILES COc1cc(CCCNc2ccc3nc(N)nc(N)c3c2Cl)cc(OC)c1OC

InChI Key InChIKey=LOARZBOONBWPPR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035480   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50035480(5-Chloro-N*6*-[3-(3,4,5-trimethoxy-phenyl)-propyl]...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50035480(5-Chloro-N*6*-[3-(3,4,5-trimethoxy-phenyl)-propyl]...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50035480(5-Chloro-N*6*-[3-(3,4,5-trimethoxy-phenyl)-propyl]...)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of Dihydrofolate reductase of Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed