BDBM50035482 5-Chloro-N*6*-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-quinazoline-2,4,6-triamine::CHEMBL141417

SMILES COc1cc(CCNc2ccc3nc(N)nc(N)c3c2Cl)cc(OC)c1OC

InChI Key InChIKey=XOXPFVFHSLDXFI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035482   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50035482(5-Chloro-N*6*-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50035482(5-Chloro-N*6*-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50035482(5-Chloro-N*6*-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of Dihydrofolate reductase of Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed