BDBM50035526 CHEMBL3343621

SMILES Cc1cc(\C=N\NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3sccc3n2)cc(C)c1O

InChI Key InChIKey=RSMAHTSDYGXRPV-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50035526   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 27nMAssay Description:Inhibition of purified PI3Kalpha (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 770nMAssay Description:Inhibition of purified mTOR (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of purified B-Raf (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of purified C-Raf (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of purified EGFR (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of purified VEGFR (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of purified PDGFRbeta (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of purified FLT3 (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of purified KIT (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035526(CHEMBL3343621)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of purified KDR (unknown origin) after 30 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed