BDBM50035748 Azetidin-1-yl-[3-(4-chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl]-methanone::CHEMBL338220

SMILES CN1C2CCC1C(C(C2)c1ccc(Cl)cc1)C(=O)N1CCC1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035748   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035748(Azetidin-1-yl-[3-(4-chloro-phenyl)-8-methyl-8-aza-...)
Affinity DataIC50: 6.60nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035748(Azetidin-1-yl-[3-(4-chloro-phenyl)-8-methyl-8-aza-...)
Affinity DataIC50: 814nMAssay Description:Binding affinity at the Serotonin transporter in rat midbrain by inhibition of 0.5 nM [3H]-paroxetine bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035748(Azetidin-1-yl-[3-(4-chloro-phenyl)-8-methyl-8-aza-...)
Affinity DataIC50: 990nMAssay Description:Binding affinity at the Norepinephrine transporter in rat frontal cortex by inhibition of 0.5 nM [3H]nisoxetine bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed