BDBM50036038 ((S)-2-Methyl-1-{(S)-2-[(S)-2-methyl-1-(thiophene-2-carbonyl)-propylcarbamoyl]-pyrrolidine-1-carbonyl}-propyl)-carbamic acid benzyl ester::CHEMBL168120

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)c1cccs1

InChI Key InChIKey=VSKWRERQCRJUIU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036038   

TargetNeutrophil elastase(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50036038(((S)-2-Methyl-1-{(S)-2-[(S)-2-methyl-1-(thiophene-...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50036038(((S)-2-Methyl-1-{(S)-2-[(S)-2-methyl-1-(thiophene-...)
Affinity DataKi:  4.30E+3nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE) catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala- Ala-Pro-Val-pNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed