BDBM50036064 2-(6-Methoxy-1-oxo-1,9-dihydro-beta-carbolin-2-yl)-N-(3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)-acetamide::CHEMBL173410

SMILES COc1ccc2nc3c(O)n(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)ccc3c2c1

InChI Key InChIKey=DRPPUXYMYMFREC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036064   

TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036064(2-(6-Methoxy-1-oxo-1,9-dihydro-beta-carbolin-2-yl)...)
Affinity DataKi:  350nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE) mediated hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-pNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed