BDBM50036076 CHEMBL176627::Methanesulfonic acid 1-oxo-3-phenyl-2-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-2,9-dihydro-1H-beta-carbolin-8-yl ester

SMILES CC(C)C(NC(=O)Cn1c(O)c2nc3c(OS(C)(=O)=O)cccc3c2cc1-c1ccccc1)C(=O)C(F)(F)F

InChI Key InChIKey=OESQQLWRZZSTIX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036076   

TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036076(Methanesulfonic acid 1-oxo-3-phenyl-2-[(3,3,3-trif...)
Affinity DataKi:  15nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE) mediated hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-pNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed