BDBM50036103 CHEMBL11098::{2-(4-Fluoro-phenyl)-6-oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-1,6-dihydro-pyrimidin-5-yl}-carbamic acid benzyl ester

SMILES CC(C)C(NC(=O)Cn1c(ncc(NC(=O)OCc2ccccc2)c1=O)-c1ccc(F)cc1)C(=O)C(F)(F)F

InChI Key InChIKey=DDFRKODWAPYUPJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036103   

TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50036103({2-(4-Fluoro-phenyl)-6-oxo-1-[(3,3,3-trifluoro-1-i...)
Affinity DataKi:  8.20nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50036103({2-(4-Fluoro-phenyl)-6-oxo-1-[(3,3,3-trifluoro-1-i...)
Affinity DataKi:  8.20nMAssay Description:In vitro inhibition of human leukocyte elastase mediated hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-pNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed