BDBM50036710 3-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-1-(2-fluoro-phenyl)-propan-1-one::CHEMBL435211

SMILES Fc1ccccc1C(=O)CCN1CCC(=CC1)c1ccc(Cl)cc1

InChI Key InChIKey=SAJIEHIWVVUUEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036710   

TargetSigma non-opioid intracellular receptor 1(Human)
New York University

Curated by ChEMBL
LigandPNGBDBM50036710(3-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...)
Affinity DataIC50: 400nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]haloperidol in the presence of 25 nM unlabeled spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
New York University

Curated by ChEMBL
LigandPNGBDBM50036710(3-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity against Dopamine receptor D2 in bovine striatal homogenate using 200 pM [3H]- spiperone and 250 nM unlabeled ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed