BDBM50036726 3-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-1-(3,4-dimethoxy-phenyl)-propan-1-one::CHEMBL126086

SMILES COc1ccc(cc1OC)C(=O)CCN1CCC(=CC1)c1ccc(Cl)cc1

InChI Key InChIKey=OTFCAEHQGHXHIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036726   

TargetSigma non-opioid intracellular receptor 1(Human)
New York University

Curated by ChEMBL
LigandPNGBDBM50036726(3-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...)
Affinity DataIC50: 495nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]haloperidol in the presence of 25 nM unlabeled spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
New York University

Curated by ChEMBL
LigandPNGBDBM50036726(3-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity against Dopamine receptor D2 in bovine striatal homogenate using 200 pM [3H]- spiperone and 250 nM unlabeled ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed