BDBM50036793 2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phenyl]-N-[(R)-1-(3-phenyl-propylcarbamoyl)-ethyl]-propionamide::CHEMBL354641

SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(OCc2ccc(F)cc2)cc1C)C(=O)NCCCc1ccccc1

InChI Key InChIKey=JXUBHIQHTFPUFA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50036793   

TargetMu-type opioid receptor(Rat)
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50: 8.70nMAssay Description:Inhibitory concentration was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50: 17.5nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50: 367nMAssay Description:Inhibitory concentration was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50: 367nMAssay Description:Inhibitory concentration was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibitory concentration was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed