BDBM50037330 CHEMBL326616::{2-Oxo-6-((E)-styryl)-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-1,2-dihydro-pyridin-3-yl}-carbamic acid benzyl ester

SMILES CC(C)C(NC(=O)Cn1c(\C=C\c2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F

InChI Key InChIKey=JJESMGOLRVHSAK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037330   

TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037330({2-Oxo-6-((E)-styryl)-1-[(3,3,3-trifluoro-1-isopro...)
Affinity DataKi:  33nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037330({2-Oxo-6-((E)-styryl)-1-[(3,3,3-trifluoro-1-isopro...)
Affinity DataKi:  5.80E+3nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed