BDBM50039004 (S)-2-({5-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5-yl)-propylamino]-thiazole-2-carbonyl}-amino)-pentanedioic acid::CHEMBL294768

SMILES Nc1nc(N)c(CCCNc2cnc(s2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)c(=O)[nH]1

InChI Key InChIKey=AYSIPLPKKFUMDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50039004   

TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039004((S)-2-({5-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimi...)
Affinity DataIC50: 140nMAssay Description:Ability to inhibit glycinamide ribonucleotide transformylase (GAR-Tfase) in vitro, using hog liver with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed