BDBM50039010 (S)-2-[(S)-2-(4-Guanidino-butyrylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid ((1S,2R)-1-cyclohexylmethyl-2-hydroxy-2-thiazol-2-yl-ethyl)-amide::CHEMBL308232

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CCCNC(N)=N)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)c1nccs1

InChI Key InChIKey=YVAMEIZCNLFMMR-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50039010   

TargetProthrombin(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50039010((S)-2-[(S)-2-(4-Guanidino-butyrylamino)-3-phenyl-p...)
Affinity DataKi:  22nMAssay Description:Binding affinity for thrombin was reportedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50039010((S)-2-[(S)-2-(4-Guanidino-butyrylamino)-3-phenyl-p...)
Affinity DataIC50: 120nMAssay Description:In vitro activity against thrombin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50039010((S)-2-[(S)-2-(4-Guanidino-butyrylamino)-3-phenyl-p...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro activity against trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50039010((S)-2-[(S)-2-(4-Guanidino-butyrylamino)-3-phenyl-p...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro activity against Factor Xa was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50039010((S)-2-[(S)-2-(4-Guanidino-butyrylamino)-3-phenyl-p...)
Affinity DataIC50: 1.43E+5nMAssay Description:In vitro activity against plasmin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed