BDBM50039042 5,7-Dimethoxy-3-thiophen-3-yl-quinoline::CHEMBL66071

SMILES COc1cc(OC)c2cc(cnc2c1)-c1ccsc1

InChI Key InChIKey=OOSYGDRIWJDGFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039042   

TargetPlatelet-derived growth factor receptor alpha/beta(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039042(5,7-Dimethoxy-3-thiophen-3-yl-quinoline | CHEMBL66...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.025-0.03More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039042(5,7-Dimethoxy-3-thiophen-3-yl-quinoline | CHEMBL66...)
Affinity DataIC50: 2.00E+4nMAssay Description:Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed