BDBM50039052 6,7-Dimethoxy-3-[(E)-2-(4-methoxy-phenyl)-vinyl]-quinoline::CHEMBL66101

SMILES COc1ccc(\C=C\c2cnc3cc(OC)c(OC)cc3c2)cc1

InChI Key InChIKey=QGIQAOODDVIYMZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039052   

TargetPlatelet-derived growth factor receptor alpha/beta(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039052(6,7-Dimethoxy-3-[(E)-2-(4-methoxy-phenyl)-vinyl]-q...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.03-0.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039052(6,7-Dimethoxy-3-[(E)-2-(4-methoxy-phenyl)-vinyl]-q...)
Affinity DataIC50: 2.00E+4nMAssay Description:Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed