BDBM50039078 3-(3-Chloro-thiophen-2-yl)-6,7-dimethoxy-quinoline::CHEMBL306234

SMILES COc1cc2cc(cnc2cc1OC)-c1sccc1Cl

InChI Key InChIKey=KYBWLWWAINBJFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039078   

TargetPlatelet-derived growth factor receptor alpha/beta(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039078(3-(3-Chloro-thiophen-2-yl)-6,7-dimethoxy-quinoline...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of isolated human PDGF receptor phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039078(3-(3-Chloro-thiophen-2-yl)-6,7-dimethoxy-quinoline...)
Affinity DataIC50: 2.00E+4nMAssay Description:Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed