BDBM50039736 CHEMBL328119::Trifluoro-methanesulfonic acid 3-((S)-1-phenethyl-piperidin-3-yl)-phenyl ester

SMILES FC(F)(F)S(=O)(=O)Oc1cccc(c1)[C@@H]1CCCN(CCc2ccccc2)C1

InChI Key InChIKey=GHZCAYNGRYIDPW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50039736   

TargetD(3) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039736(Trifluoro-methanesulfonic acid 3-((S)-1-phenethyl-...)
Affinity DataKi:  19nMAssay Description:Tested for in vitro binding affinity against cloned mammalian dopamine autoreceptor (DA) receptors expressed in CHO-K1 cells [3H]-spiperone as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039736(Trifluoro-methanesulfonic acid 3-((S)-1-phenethyl-...)
Affinity DataKi:  40nMAssay Description:Tested for affinity against striatal dopamine autoreceptor (DA) D2 receptors using [3H]spiperone as radioligand in rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039736(Trifluoro-methanesulfonic acid 3-((S)-1-phenethyl-...)
Affinity DataKi:  73nMAssay Description:Affinity against recombinant dopamine receptor (DA) D2 expressed in CHO-K1 cells, using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed