BDBM50039767 CHEMBL92630::Toluene-4-sulfonic acid 3-((S)-1-propyl-piperidin-3-yl)-phenyl ester

SMILES CCCN1CCC[C@H](C1)c1cccc(OS(=O)(=O)c2ccc(C)cc2)c1

InChI Key InChIKey=HFJQAHIKNXSVRM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039767   

TargetD(3) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039767(Toluene-4-sulfonic acid 3-((S)-1-propyl-piperidin-...)
Affinity DataKi:  92nMAssay Description:Tested for in vitro binding affinity against cloned mammalian dopamine autoreceptor (DA) receptors expressed in CHO-K1 cells [3H]-spiperone as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039767(Toluene-4-sulfonic acid 3-((S)-1-propyl-piperidin-...)
Affinity DataKi: >217nMAssay Description:Affinity against recombinant dopamine receptor (DA) D2 expressed in CHO-K1 cells, using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039767(Toluene-4-sulfonic acid 3-((S)-1-propyl-piperidin-...)
Affinity DataKi:  1.32E+3nMAssay Description:Tested for affinity against striatal dopamine autoreceptor (DA) D2 receptors using [3H]spiperone as radioligand in rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039767(Toluene-4-sulfonic acid 3-((S)-1-propyl-piperidin-...)
Affinity DataKi:  1.60E+3nMAssay Description:Tested for affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in homogenized rat brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed