BDBM50039847 CHEMBL3357877

SMILES CCc1cc(Nc2ncc(cc2-c2nc(C)nc(N)n2)C(C)(C)O)cnc1OC

InChI Key InChIKey=BQJPZFLREHORGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50039847   

TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50039847(CHEMBL3357877)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of recombinant N-terminally GST-tagged mTOR (1360 to 2549 aa) (unknown origin) assessed as inhibition of 27BP1 phosphorylation after 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed