BDBM50039947 2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine::CHEMBL97450

SMILES CCCCCCCCCOc1ccc2[nH]cc(CCN)c2c1

InChI Key InChIKey=YHSMSRREJYOGQJ-UHFFFAOYSA-N

Data  7 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50039947   

Target5-hydroxytryptamine receptor 1D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50039947(2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine | CHEMBL97...)
Affinity DataEC50:  68nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1D-beta receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1B(Human)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50039947(2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine | CHEMBL97...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 1D receptor beta in CHO cells transfected with human 5-HT1D beta gene labeled with [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50039947(2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine | CHEMBL97...)
Affinity DataKi:  13nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 1B receptor in rat striatum labeled with [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50039947(2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine | CHEMBL97...)
Affinity DataKi:  16nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 1D receptor alpha in COS cells transfected with human 5-HT1D alpha gene labeled with [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50039947(2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine | CHEMBL97...)
Affinity DataKi:  260nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 2A receptor in GF6 cells transfected with human 5-HT2A gene labeled with [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50039947(2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine | CHEMBL97...)
Affinity DataKi:  270nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 2C receptor in J1 cells transfected with rat 5-HT2C gene labeled with [3H]mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50039947(2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine | CHEMBL97...)
Affinity DataKi:  315nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 1A receptor in AK cells transfected with human 5-HT1A gene labeled with [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50039947(2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine | CHEMBL97...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 3 receptor in NG-108 cells labeled with [3H]GR-65630More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed