BDBM50040132 CHEMBL411196::Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-(D-Pro)-Lys-Leu-Cys)

SMILES CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=GRCXYAMUGBVXNL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50040132   

TargetKappa-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040132(Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-(D-Pro)-Lys-...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of [3H]U-69593 binding to kappa opioid receptor of guinea pig brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040132(Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-(D-Pro)-Lys-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [3H]PL-17 binding to mu opioid receptor of guinea pig brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040132(Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-(D-Pro)-Lys-...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of [3H]DPDPE binding to delta opioid receptor of guinea pig brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040132(Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-(D-Pro)-Lys-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of mu-selective antagonist binding to opioid receptor of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040132(Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-(D-Pro)-Lys-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of delta-selective antagonist binding to opioid receptor of mouse vas dferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed