BDBM50040134 CHEMBL2371443::Tyr-Gly-Gly-(L-Tic)-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys)

SMILES [H][C@]12[#6]-[#6]-[#6]-[#7]1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)[C@]([H])([#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#16]-[#16]-[#6]-[#6@@H](-[#7]-[#6]2=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-c2ccccc2-[#6]-[#7]-1-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)[#6@@H](-[#6])-[#6]-[#6]

InChI Key InChIKey=IHEBXHWDGDWBNX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50040134   

TargetKappa-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040134(Tyr-Gly-Gly-(L-Tic)-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys)...)
Affinity DataIC50: 52nMAssay Description:Inhibition of [3H]U-69593 binding to kappa opioid receptor of guinea pig brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040134(Tyr-Gly-Gly-(L-Tic)-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys)...)
Affinity DataIC50: 106nMAssay Description:Inhibition of [3H]PL-17 binding to mu opioid receptor of guinea pig brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040134(Tyr-Gly-Gly-(L-Tic)-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys)...)
Affinity DataIC50: 181nMAssay Description:Inhibition of [3H]DPDPE binding to delta opioid receptor of guinea pig brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040134(Tyr-Gly-Gly-(L-Tic)-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys)...)
Affinity DataIC50: 4.18E+3nMAssay Description:Inhibition of delta-selective antagonist binding to opioid receptor of mouse vas dferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50040134(Tyr-Gly-Gly-(L-Tic)-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys)...)
Affinity DataIC50: 6.18E+3nMAssay Description:Inhibition of mu-selective antagonist binding to opioid receptor of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed