BDBM50040281 CHEMBL105645::CHEMBL543134::cis-7-Dimethylamino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide::trans-7-Dimethylamino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide

SMILES CN(C)C1CC(c2ccccc2)c2cc(O)c(O)cc2C1

InChI Key InChIKey=IFDQCFBQHUVXHV-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50040281   

TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 6.20nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 6.20nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 34nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 34.3nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity against dopamine receptor D2 from rat striatal homogenates using [3H]YM-09151-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity against dopamine receptor D2 from rat striatal homogenates using [3H]YM-09151-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using [3H]ditolylguanidine (DTG) as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against dopamine receptor D1 from rat striatal homogenates, using [3H]SCH-23,390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using [3H]ditolylguanidine (DTG) as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040281(CHEMBL105645 | cis-7-Dimethylamino-5-phenyl-5,6,7,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against dopamine receptor D1 from rat striatal homogenates, using [3H]SCH-23390 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed