BDBM50040854 11-(2,6-Diisopropyl-phenylcarbamoyl)-2-methyl-6,11-dihydro-dibenzo[b,e]oxepine-4-carboxylic acid methyl ester::CHEMBL167205

SMILES COC(=O)c1cc(C)cc2C(C(=O)Nc3c(cccc3C(C)C)C(C)C)c3ccccc3COc12

InChI Key InChIKey=LRCLMLRBNOVJSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040854   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50040854(11-(2,6-Diisopropyl-phenylcarbamoyl)-2-methyl-6,11...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in liver microsomes isolated from cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed