BDBM50041053 2-[3-(3,4-Difluoro-phenyl)-2-mercaptomethyl-butyrylamino]-propionic acid::CHEMBL276008

SMILES CC(NC(=O)C(CS)C(C)c1ccc(F)c(F)c1)C(O)=O

InChI Key InChIKey=ATOXZPUMMFMOBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041053   

TargetAngiotensin-converting enzyme(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50041053(2-[3-(3,4-Difluoro-phenyl)-2-mercaptomethyl-butyry...)
Affinity DataIC50: 5nMAssay Description:Inhibitory potency against angiotensin converting enzyme by displacement of [3H]trandolaprilate binding in mouse lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50041053(2-[3-(3,4-Difluoro-phenyl)-2-mercaptomethyl-butyry...)
Affinity DataIC50: 3.5nMAssay Description:In vivo inhibitory potency against neutral endopeptidase by displacement of [3H]HACBOGly binding in mouse kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed