BDBM50041075 CHEMBL3355417

SMILES O[C@H]1CC[C@@H](CC1)NC(=O)[C@@H]1NC2(CCCCCC2)[C@]2([C@H]1c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)ccc21

InChI Key InChIKey=UVWMOYGSAUBCGS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041075   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50041075(CHEMBL3355417)
Affinity DataIC50: 16nMAssay Description:Binding affinity to human His-tagged MDM2 (1 to 118 residues) using FAM tagged p53-based peptide by fluorescence prolarization based protein binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50041075(CHEMBL3355417)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to human His-tagged MDM2 (1 to 118 residues) using FAM tagged p53-based peptide by fluorescence prolarization based protein binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed