BDBM50041180 5-[(2,5-Dimethoxy-phenylamino)-methyl]-furo[2,3-d]pyrimidine-2,4-diamine::CHEMBL17044

SMILES COc1ccc(OC)c(NCc2coc3nc(N)nc(N)c23)c1

InChI Key InChIKey=PKKNZBRQGXNJCE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50041180   

TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041180(5-[(2,5-Dimethoxy-phenylamino)-methyl]-furo[2,3-d]...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration for DHFR in recombinant humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041180(5-[(2,5-Dimethoxy-phenylamino)-methyl]-furo[2,3-d]...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory concentration for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041180(5-[(2,5-Dimethoxy-phenylamino)-methyl]-furo[2,3-d]...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory concentration for DHFR in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041180(5-[(2,5-Dimethoxy-phenylamino)-methyl]-furo[2,3-d]...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory concentration for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041180(5-[(2,5-Dimethoxy-phenylamino)-methyl]-furo[2,3-d]...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibitory concentration for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed