BDBM50041320 4-Hydroxy-2-[1-pyridin-4-yl-meth-(E)-ylidene]-indan-1-one::CHEMBL284934

SMILES Oc1cccc2C(=O)\C(Cc12)=C\c1ccncc1

InChI Key InChIKey=BQBDUNUCJDXMNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041320   

TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50041320(4-Hydroxy-2-[1-pyridin-4-yl-meth-(E)-ylidene]-inda...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human Placental Cytochrome P450 19A1 in vitro using human placental microsomes and testosteroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50041320(4-Hydroxy-2-[1-pyridin-4-yl-meth-(E)-ylidene]-inda...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of TNFalpha (unknown origin)-induced adhesion of BCECF fluorescence-labeled human U937 cells to human HT-29 cells measured at 3 hrs post T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2020
Entry Details Article
PubMed