BDBM50041670 2-{4-[2-(2-Amino-4-hydroxy-6,7-dihydro-5H-cyclopentapyrimidin-5-yl)-ethyl]-benzoylamino}-pentanedioic acid::CHEMBL296190

SMILES Nc1nc2CCC(CCc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)c2c(=O)[nH]1

InChI Key InChIKey=UHHNBPRUPMUDTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041670   

TargetDihydrofolate reductase(Mouse)
Eisai

Curated by ChEMBL
LigandPNGBDBM50041670(2-{4-[2-(2-Amino-4-hydroxy-6,7-dihydro-5H-cyclopen...)
Affinity DataIC50: 2.10nMAssay Description:Compound was tested for the inhibition of dihydrofolate reductase in P388 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed