BDBM50041672 2-{4-[3-(2,4-Diamino-6,7-dihydro-5H-cyclopentapyrimidin-5-yl)-propyl]-benzoylamino}-pentanedioic acid::CHEMBL41056

SMILES Nc1nc2CCC(CCCc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)c2c(N)n1

InChI Key InChIKey=DSPMDRAVVJOBBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041672   

TargetDihydrofolate reductase(Lactobacillus casei)
Eisai

Curated by ChEMBL
LigandPNGBDBM50041672(2-{4-[3-(2,4-Diamino-6,7-dihydro-5H-cyclopentapyri...)
Affinity DataIC50: 2.5nMAssay Description:Compound was tested for the inhibition of dihydrofolate reductase in Bovine liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Eisai

Curated by ChEMBL
LigandPNGBDBM50041672(2-{4-[3-(2,4-Diamino-6,7-dihydro-5H-cyclopentapyri...)
Affinity DataIC50: 7.10nMAssay Description:Compound was tested for the inhibition of dihydrofolate reductase in P388 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed