BDBM50041946 1N-(2,2,2-trifluoroethyl)-2-benzylcarboxamido-2-[4-{2-[2-benzylcarboxamido(2,2,2-trifluoroethylcarbamoyl)methyl-5,5-dimethyl-(2R,4S)-1,3-thiazolan-4-ylcarboxamido]ethylcarbamoyl}-3,5,5-trimethyl-(2S,4S)-tetrahydro-2-thiophenyl]acetamide::CHEMBL432969

SMILES CC1(C)S[C@@H](NC1C(=O)NCCNC(=O)[C@@H]1N[C@H](SC1(C)C)[C@H](NC(=O)Cc1ccccc1)C(=O)NCC(F)(F)F)[C@H](NC(=O)Cc1ccccc1)C(=O)NCC(F)(F)F

InChI Key InChIKey=SRJPSKNGOVFEQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041946   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50041946(1N-(2,2,2-trifluoroethyl)-2-benzylcarboxamido-2-[4...)
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed